Showing 3 results for Dehghani
Farzane Farokhi, Javad Razaviyan, Mehrnoush Kosaryan, Mostafa Roudbari, Samira Esmaeili Reykande, Aily Aliasghariyan, Maryam Dehghani,
Volume 4, Issue 3 (September 2015)
Abstract
Abstract Background: Beta thalassemia is an inherited disorder characterized by absent or reduced amounts of beta globin chains. Vascular Endothelial Growth Factor (VEGF) is a significant regulator of hemangioblast differentiation. This study was aimed to assess serum VEGF levels in patients with beta thalassemia major in comparison with control group. Methods: This historical cohort study was conducted on 36 patients with β–thalassemia major who had received regular blood transfusion and 26 healthy people which were referred for checkup in a general hospital, Sari, north of Iran, during March to May 2015. Demographic characterization and laboratory tests such as Complete Blood Count (CBC), and evaluation of levels of serum ferritin, serum VEGF, hepatitis B virus antibody and hepatitis C virus antibody were carried out for our patients. The statistical analyses were performed by SPSS (16) software. The Pearson correlation coefficient test was used to test the significant correlations for quantitative parameters. A value of P<0.05 was considered statistically significant. Results: Mean serum VEGF level in case and control groups was 153.8 ± 77.5 and 120.2± 45.4 pg/ml, respectively. Serum VEGF level was higher in beta thalassemia major (p= 0.037). Serum VEGF level was significantly higher in splenectomized patients (P=0.006). There was not any significant correlation between serum VEGF levels and Hemoglobin, WBC and platelet count and neither was with serum ferritin level (p>0.05). Conclusion: Serum VEGF level was higher in thalassemic patients. Splenectomized patients had higher serum VEGF levels than others.
Fatemeh Mallah, Abbasali Dehghani,
Volume 10, Issue 3 (9-2021)
Abstract
Introduction: Intratracheal intubation has many side effects in people who have difficulty intubating, the most common of which is hoarseness and sore throat; Therefore, it is necessary to prevent it. The aim of this study was to investigate the effects of rosemary on voice violence and sore throat after endotracheal intubation in women with difficult intubation.
Methods: This study was a randomized Non-blind clinical trial in which during 2018, with the participation of 70 patients undergoing general anesthesia, they were randomly(Randomly Permuted Block) divided into two groups: control (inserting sterile gauze impregnated with distilled water into the patient's throat) and intervention (inserting sterile gas impregnated with rosemary into the patient's throat). Sore throat and voice violence were measured using VAS scale and finally the data were entered in SPSS20 software and analyzed by descriptive and inferential statistics.
Results: The severity of sore throat in the intervention group(49.77±4.77 ) was not significantly(p=0.6) less than the severity of the control group(53.20±4.93); The need for treatment was not observed in either group.
Conclusion: Rosemary extract could not reduce noise and sore throat after intubation in people with difficult intubation.
Zhila Rahmanian, Khaterh Dehghani, Ehsan Habibi, Mohammad Sadegh Sanie Jahromi, Lohrasb Taheri, Elahe Rahmanian, Samaneh Abiri,
Volume 12, Issue 1 (3-2023)
Abstract
Inflammatory factors play a very important role in causing inflammation. These inflammatory factors and proteins are the regulators of inflammatory responses. Considering the high transmission power and the pandemic caused by COVID-19, it is necessary and important to determine the effective factors in the prognosis of this disease.
Method: This study was carried out by descriptive method and based on secondary data analysis in the files of hospitalized patients with covid-19 in the first six months of 2021 by census method. The data collection tool is a checklist (data collection form). Three categories of variables including epidemiological variables, clinical variables, and laboratory variables were extracted from the patient's files and analyzed.
Results: The data of 302 patients with COVID-19 hospitalized in the ICU department of Peymaniyeh Hospital were collected. The majority of patients were over 50 years old. There was no significant relationship between the severity of the disease and all of the demographic, clinical, and laboratory variables (P>0.05), except for the number of hospitalization days that in patients with severe disease, severity was significantly higher than in patients with moderate disease severity (P=0.001); CRP, ERS, and LDH in patients with severe disease severity were significantly higher than patients with moderate disease severity (P<0.05); But there was no significant relationship between other laboratory characteristics and disease severity (P<0.05).
Conclusion: It can be concluded that patients over 50 years of age who are admitted to the ICU require more careful care and elderly patients may have a higher chance of contracting COVID-19.
