Objective: Hemodialysis is a treatment for End Stage Renal Disease (ESRD) patients. The incidence of ESRD has been increased up to 8% from 2004 to 2011. Based on some studies, various complications can occur in hemodialysis process. This study was conducted with the aim of investigating the incidence of adverse side-effects during hemodialysis in kidney patients.

Methods: This descriptive-analytical study was done in 2015 (05 Feb to 12 April) on 142 patients under hemodialysis treatment. Data gathering was done by using a researcher-made checklist which was designed by studying authoritative sources. Data analysis was done by SPSS. V.16  using ANOVA and Chi-square tests.

Results: Among 142 patients, 51.38% were female and 48.62 of them were male. Muscle cramp (72.53%) and Bleeding (2.11%) were the most and the least complications that have been attested during hemodialysis respectively.

Conclusion: According to the various side-effects of hemodialysis process in this study, some actions such as reducing the pump rotation and nutrition education is recommended in order to increase the level of satisfaction in patients.